Research Article
Published: 14 October, 2020 | Volume 3 - Issue 2 | Pages: 127-131
Aim and objectives: The primary aim was to measure the sperm DNA damage and to study the magnitude of sperm DNA damage. Secondary objective was to study the effect of sperm DNA fragmentation on Day 5 Blastocyst expansion (graded 1-5).
Results: There is an increase in sperm DNA fragmentation with an increase in age. Increased sperm DNA fragmentation is also associated with abnormal motility and morphology in semen samples. However, there is no reduction in expansion or grade of blastocyst.
Conclusion: Sperm DNA fragmentation testing is a useful investigation in unexplained infertility. However, Sperm DNA fragmentation has no significant association with Day 5 embryo grade in ICSI cycles.
Thesis work of Fellowship in Reproductive Medicine student: Dr. Ramya Harish
Read Full Article HTML DOI: 10.29328/journal.cjog.1001065 Cite this Article Read Full Article PDF
Sperm; DNA; Embryo; Assisted reproductive technology; Blastocyst; ICSI
HSPI: We're glad you're here. Please click "create a new Query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."